How to Improve Oral Health & Its Critical Role in Brain & Body Health


Huberman Lab

In this episode, I discuss the importance of oral health for dental and microbiome health and general physical and mental well-being. I explain science-supported protocols for strengthening your teeth and gums, including how to remineralize your teeth. I cover the best approaches and timing for brushing and flossing, tongue, gum, and oral microbiome care and how oral health is critically important to offset metabolic, cardiac, and brain diseases, including dementia. I also discuss proper nutrition for oral health, fluoride, and how sugar and mouth breathing can accelerate tooth decay. This episode ought to be of interest to everyone seeking to improve their physical health, mental health, and lifespan, given the critical role that oral health plays in all of these.

For show notes, including referenced articles and additional resources, please visit

Thank you to our sponsors​




Helix Sleep:




(00:00:00) Oral Health

(00:03:28) Sponsors: Mateina, ROKA & Helix Sleep

(00:07:13) Oral Health Quiz

(00:13:53) Teeth Biology, Cavity Repair

(00:20:01) Mouth, Gums, Saliva

(00:27:23) Sponsor: AG1

(00:28:51) Cavity Formation, Bacteria, Sugar, Acidity

(00:35:10) Teeth Remineralization, Fluoride, Water

(00:42:57) Sponsor: InsideTracker

(00:43:58) Tools: The “Do Nots” of Oral Health, Mouth Breathing

(00:54:48) Tools: Fasting & Teeth Remineralization; Nighttime Toothbrushing

(01:03:23) Proper Teeth Brushing; Tooth Sensitivity & Gums

(01:08:16) Bacteria, Plaque & Tartar; Tooth Polishing

(01:11:02) Proper Flossing Technique, Waterpik; Children & Flossing

(01:14:23) Tool: Xylitol, Bacteria & Cavity Prevention

(01:19:43) Toothpastes: Xylitol, Fluoride, Hydroxyapatite

(01:22:38) Mouthwash & Alcohol, Antiseptic Mouthwash

(01:26:29) Tools: Baking Soda, Hydrogen Peroxide?, Salt Water Rinse

(01:32:36) Alcohol-Based Mouthwash, Nitric Oxide

(01:34:52) Tools: Canker Sore Prevention & Gut Microbiome; Sleep

(01:37:47) Tools: Tongue Brushing; Toothbrush Care

(01:41:38) Teeth Sealants; Metal Fillings, Mercury, Mastic Gum; Root Canals

(01:48:43) Dentist Visits, Daily Routines & Oral Health

(01:54:17) Practices for Oral Health, Oil Pulling

(01:58:21) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter


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